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Boswellic Acid 90 percent in Ta Khmau

In 80% human plasma (in vitro) and rat blood (in vivo) also 96.35% and 91% release of rhein and 78% and 86.41% release of boswellic acid respectively was observed. the 24h pooled samples of rat urine revealed presence of 6.2% intact prodrug, 7.1% of rhein and 8.9% of boswellic acid indicating their renal excretion.
Boswellic acid is a mixture of pentacyclic triterpenes including beta- boswellic acid, 3-acteyl beta-boswellic acid, 11-keto-beta-boswellic acid and acetyl-11-keto-beta-boswellic acid
Our results have indicated an increase (35–50%) in cyp4a‐dependent lauric acid hydroxylation in liver, kidney, and brain of diabetic rats. about a two‐fold increase in cyp2e‐dependent hepatic aniline hydroxylation and a 90–100% increase in cyp1a‐dependent ethoxycoumarin‐o‐deethylase activities in kidney and brain were also observed.
Solubility enhancement of boswellia serrata roxb. ex colebr. extract through a self dispersible lipidic formulation approach. ... 11-keto-β-boswellic acid ...

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