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silybum marianum p e in Cambodia

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Milk thistle (silybum marianum) is a herbal product commonly used by patients with hiv for the management or prevention of antiretroviral-induced hepatotoxicity or liver disease caused by co-infection with hepatitis b or c [27].
Silybum marianum (l.) gaertn. (asteraceae) is an annual or biennial plant native to the mediterranean region, sinai, eastwards to afghanistan, and has been naturalized in other parts of the world . the fruits of this plant are of the achene type and have a
Only 1-2% of the dose was excreted in the urine during the 24 hours following administration. after oral administration of a single dose of 140 mg silymarin (equivalent to 60mg silybin) to 14 patients who had undergone cholecystectomy, bile collected from the t-tube drains contained 11-47 µg/ml silybin

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